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Audrey Hendley, Ph.D

Audrey Hendley, Ph.D

  • Associate Specialist

Contact Information

audrey.hendley@ucsf.edu
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Biography

As an Associate Specialist in the Surgery department at UCSF, my focus rests predominantly on the intersection of genetics and molecular biology particularly in relation to pancreatic diseases. Having received a B.S. in Biology from the University of South Carolina Aiken, I pursued a PhD in Human Genetics and Molecular Biology at Johns Hopkins University School of Medicine. My work, both as a researcher and principal investigator, has centered around exploring ceramide signaling, pancreatic cancer initiation, and the potential of genetic insights in combatting cancer. This has resulted in numerous research contributions and recognition in the form of awards, signifying a career marked by a deep-rooted interest in advancing our understanding of pancreatic cancer biology.

Education & Training

  Institution  
  Degree    
  Dept or School    
  End Date    
  • Johns Hopkins Univeristy School of Medicine
  • Ph.D. Human Genetics and Molecular Biology
  • McKusick/Nathans Institute of Genetic Medicine
  • 2016
  • University of South Carolina Aiken
  • B.S. Biology (Major), Chemistry (Minor)
  • Department of Biology and Geology
  • 2009

    • Awards & Honors

      Award  
      Confired By    
      Date    
  • F32 Individual Postdoctoral Fellowship (NRSA)
  • University of California San Francisco
  • 2017 - 2019
  • APA Young Investigator Award
  • American Pancreatic Association Annual Meeting
  • 2017
  • Seed Grant Recipient, Hirshberg Foundation for Pancreatic Cancer Research
  • University of California San Francisco
  • 2016 - 2017
  • T32 Institutional National Research Service Award (NRSA)
  • University of California San Francisco
  • 2016 - 2017
  • Women in Pancreas travel award
  • American Pancreatic Association Annual Meeting
  • 2015
  • Travel Award
  • Gordon Research Conference on Pancreatic Diseases
  • 2015
  • T32 Institutional National Research Service Award (NRSA)
  • Johns Hopkins University School of Medicine
  • 2009 - 2011
  • Biology Student of the Year
  • University of South Carolina Aiken
  • 2009
  • Outstanding Senior Student
  • University of South Carolina Aiken
  • 2009
  • Magellan Research Scholarship
  • University of South Carolina
  • 2008

    • Research & Funding

    Data provided by UCSF Profiles, powered by CTSI
    ORCID iD: 0000-0003-0289-2092 Additional info
    • Molecular and Cellular Mechanisms in Cancer
      Sponsor:
      Sponsor ID:
      Funding Period:
      Sep 2004
      -
      Aug 2025
      Trainee
    • Predoctoral Training Program in Human Genetics
      Sponsor:
      Sponsor ID:
      Funding Period:
      Jul 1980
      -
      Jun 2022
      Trainee
    • Examination of ceramide signaling in the crosstalk between pancreatic cancer cells and the tumor microenvironment
      Sponsor:
      Sponsor ID:
      Funding Period:
      Dec 2017
      -
      Nov 2020
      Principal Investigator
    • Understanding sphingolipid metabolism in pancreatic cancer initiation, progression, and chemotherapeutics
      Sponsor:
      Sponsor ID:
      Funding Period:
      Nov 2016
      -
      Nov 2017
      Principal Investigator

    Publications

    MOST RECENT PUBLICATIONS FROM A TOTAL OF 17
    Data provided by UCSF Profiles, powered by CTSI
    1. Audrey M. Hendley, Atsushi Urano, Xianlu L. Peng, Sudipta Ashe, Natanya R. Kerper, Tuan A. Phu, Martin Ng, Simone Giacometti, David I. Berrios, Gun H. Jang, Jen J. Yeh, Steven Gallinger, David K. Chang, Andrew V. Biankin, Valerie M. Weaver, Grace E. Kim, David W. Dawson, Robert L. Raffai, Matthias Hebrok. Abstract C051: Ceramide signaling regulates PDA aggression through exosome reprogramming of the stroma. Cancer Research. 2022 Nov 15; 82(22_Supplement):c051-c051. View in PubMed
    2. Laura Leonhardt, Lucia Y. Li, David I. Berrios, Sudipta Ashe, Audrey M. Hendley, Grace E. Kim, Matthias Hebrok. Abstract PR-008: Kdm6 demethylases are critical regulators of pancreatic cancer initiation, progression and subtype specification. Cancer Research. 2021 Nov 15; 81(22_Supplement):pr-008-pr-008. View in PubMed
    3. Audrey M. Hendley, Atsushi Urano, Natanya R. Kerper, Phat Duong, Peter Bailey, David K. Chang, Andrew V. Biankin, David W. Dawson, Grace Kim, Robert L. Raffai, Matthias Hebrok. Abstract C20: Smpd3 augments chemotherapy and thwarts PDA progression. Cancer Research. 2019 Dec 13; 79(24_Supplement):c20-c20. View in PubMed
    4. Kishore Polireddy, Audrey Hendley, Melissa A. Pruski, Kelly Lafaro, Mamoun Younes, Anirban Maitra, Florencia McAllister, Christine A. Iacobuzio-Donahue, Wasim A. Dar, John S. Bynon, Steven D. Leach, Jennifer M. Bailey. Abstract PR03: Mutant p53 promotes adenocarcinoma in pancreatic ductal cells. Early Detection. 2016 Dec 15; pr03-pr03. View in PubMed
    5. Hendley AM, Wang YJ, Polireddy K, Alsina J, Ahmed I, Lafaro KJ, Zhang H, Roy N, Savidge SG, Cao Y, Hebrok M, Maitra A, Reynolds AB, Goggins M, Younes M, Iacobuzio-Donahue CA, Leach SD, Bailey JM. p120 Catenin Suppresses Basal Epithelial Cell Extrusion in Invasive Pancreatic Neoplasia. Cancer Res. 2016 06 01; 76(11):3351-63. View in PubMed
    6. View All Publications

     

     
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