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Publications

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Friedland JC, Lakins JN, Kazanietz MG, Chernoff J, Boettiger D, Weaver VM
Expression of Concern: α6β4 integrin activates Rac-dependent p21-activated kinase 1 to drive NF-κB-dependent resistance to apoptosis in 3D mammary acini.
Journal of cell science, 2023-10-15.
Pedram K, Shon DJ, Tender GS, Mantuano NR, Northey JJ, Metcalf KJ, Wisnovsky SP, Riley NM, Forcina GC, Malaker SA, Kuo A, George BM, Miller CL, Casey KM, Vilches-Moure JG, Ferracane MJ, Weaver VM, Läubli H, Bertozzi CR
Design of a mucin-selective protease for targeted degradation of cancer-associated mucins.
Nature biotechnology, 2023-08-03.
Tharp K, Park S, Timblin G, Richards A, Twells N, Riley N, Peltan E, Shon J, Stevenson E, Tsui K, Palomba F, Lefebvre A, Soens R, Ayad N, Hoeve-Scott JT, Healy K, Digman M, Dillin A, Bertozzi C, Swaney D, Mahal L, Cantor J, Paszek M, Weaver VM, Twells N
The microenvironment dictates glycocalyx construction and immune surveillance.
Research square, 2023-08-16.
Ayad NME, Lakins JN, Ghagre A, Ehrlicher AJ, Weaver VM
Tissue tension permits β-catenin phosphorylation to drive mesoderm specification in human embryonic stem cells.
bioRxiv : the preprint server for biology, 2023-07-15.
Chan TS, Hsu CC, Pai VC, Liao WY, Huang SS, Tan KT, Yen CJ, Hsu SC, Chen WY, Shan YS, Li CR, Lee MT, Jiang KY, Chu JM, Lien GS, Weaver VM, Tsai KK
Correction: Metronomic chemotherapy prevents therapy-induced stromal activation and induction of tumor-initiating cells.
The Journal of experimental medicine, 2023-06-20.
Stashko C, Hayward MK, Northey JJ, Pearson N, Ironside AJ, Lakins JN, Oria R, Goyette MA, Mayo L, Russnes HG, Hwang ES, Kutys ML, Polyak K, Weaver VM
A convolutional neural network STIFMap reveals associations between stromal stiffness and EMT in breast cancer.
Nature communications, 2023-06-15.
Kersten K, You R, Liang S, Tharp KM, Pollack J, Weaver VM, Krummel MF, Headley MB
Uptake of tumor-derived microparticles induces metabolic reprogramming of macrophages in the early metastatic lung.
Cell reports, 2023-05-30.
Miroshnikova YA, Mouw JK, Barnes JM, Pickup MW, Lakins JN, Kim Y, Lobo K, Persson AI, Reis GF, McKnight TR, Holland EC, Phillips JJ, Weaver VM
Author Correction: Tissue mechanics promote IDH1-dependent HIF1a-tenascin C feedback to regulate glioblastoma aggression.
Nature cell biology, 2023-04-04.
Salvador F, Martin A, L?pez-Men?ndez C, Moreno-Bueno G, Santos V, V?zquez-Naharro A, Santamar?a PG, Morales S, Dubus PR, Muinelo-Romay L, L?pez-L?pez R, Tung JC, Weaver VM, Portillo F, Cano A
Correction: Lysyl Oxidase-like Protein LOXL2 Promotes Lung Metastasis of Breast Cancer.
Cancer research, 2023-03-15.
Wu B, Liu DA, Guan L, Myint PK, Chin L, Dang H, Xu Y, Ren J, Li T, Yu Z, Jabban S, Mills GB, Nukpezah J, Chen YH, Furth EE, Gimotty PA, Wells RG, Weaver VM, Radhakrishnan R, Wang XW, Guo W
Stiff matrix induces exosome secretion to promote tumour growth.
Nature cell biology, 2023-02-16.
Northey JJ, Weaver VM
Extracellular Matrix Glycation and Crosslinking in Mammary Tumor Progression.
Methods in molecular biology (Clifton, N.J.), 2023-01-01.
Gaietta G, Kai F, Swift MF, Weaver VM, Volkmann N, Hanein D
Novel cryo-tomography workflow reveals nanometer-scale responses of epithelial cells to matrix stiffness and dimensionality.
Molecular biology of the cell, 2022-10-26.
Cabral KA, Srivastava V, Graham AJ, Coyle MC, Stashko C, Weaver V, Gartner Z
Programming the Self-Organization of Endothelial Cells into Perfusable Microvasculature.
Tissue engineering. Part A, 2022-10-01.
Bell ES, Shah P, Zuela-Sopilniak N, Kim D, Varlet AA, Morival JLP, McGregor AL, Isermann P, Davidson PM, Elacqua JJ, Lakins JN, Vahdat L, Weaver VM, Smolka MB, Span PN, Lammerding J
Low lamin A levels enhance confined cell migration and metastatic capacity in breast cancer.
Oncogene, 2022-07-27.
Kai F, Ou G, Tourdot RW, Stashko C, Gaietta G, Swift MF, Volkmann N, Long AF, Han Y, Huang HH, Northey JJ, Leidal AM, Viasnoff V, Bryant DM, Guo W, Wiita AP, Guo M, Dumont S, Hanein D, Radhakrishnan R, Weaver VM
ECM dimensionality tunes actin tension to modulate endoplasmic reticulum function and spheroid phenotypes of mammary epithelial cells.
The EMBO journal, 2022-07-25.
Northey JJ, Weaver VM
Mechanosensitive steroid hormone signaling and cell fate.
Endocrinology, 2022-06-09.
Tsai KK, Huang SS, Northey JJ, Liao WY, Hsu CC, Cheng LH, Werner ME, Chuu CP, Chatterjee C, Lakins JN, Weaver VM
Screening of organoids derived from patients with breast cancer implicates the repressor NCOR2 in cytotoxic stress response and antitumor immunity.
Nature cancer, 2022-05-26.
Metcalf KJ, Hayward MK, Berens E, Ironside AJ, Stashko C, Hwang ES, Weaver VM
Immunosuppressive glycoproteins associate with breast tumor fibrosis and aggression.
Matrix biology plus, 2022-03-09.
Samson S, Northey JJ, Acerbi I, Goga A, Flink CL, Weaver VM, LaBarge MA
NCI's publication affiliation conundrum: Reframing innovation to incentivize an equitable path for advocate representation.
Translational oncology, 2021-12-30.
Weaver VM
Mechanobiology: forcing the second act.
Molecular biology of the cell, 2021-08-19.
EPH/EPHRIN regulates cellular organization by actomyosin contractility effects on cell contacts.
The Journal of cell biology, 2021-06-07.
Hayward MK, Muncie JM, Weaver VM
Tissue mechanics in stem cell fate, development, and cancer.
Developmental cell, 2021-06-03.
Rudnick JA, Monkkonen T, Mar FA, Barnes JM, Starobinets H, Goldsmith J, Roy S, Bustamante Eguiguren S, Weaver VM, Debnath J
Autophagy in stromal fibroblasts promotes tumor desmoplasia and mammary tumorigenesis.
Genes & development, 2021-06-24.
Matrix compliance permits NF-?B activation to drive therapy resistance in breast cancer.
The Journal of experimental medicine, 2021-05-03.
Tharp KM, Higuchi-Sanabria R, Timblin GA, Ford B, Garzon-Coral C, Schneider C, Muncie JM, Stashko C, Daniele JR, Moore AS, Frankino PA, Homentcovschi S, Manoli SS, Shao H, Richards AL, Chen KH, Hoeve JT, Ku GM, Hellerstein M, Nomura DK, Saijo K, Gestwicki J, Dunn AR, Krogan NJ, Swaney DL, Dillin A, Weaver VM
Adhesion-mediated mechanosignaling forces mitohormesis.
Cell metabolism, 2021-05-17.
Hayward MK, Weaver VM
Improving DCIS diagnosis and predictive outcome by applying artificial intelligence.
Biochimica et biophysica acta. Reviews on cancer, 2021-04-29.
Metcalf KJ, Alazzeh A, Werb Z, Weaver VM
Leveraging microenvironmental synthetic lethalities to treat cancer.
The Journal of clinical investigation, 2021-03-15.
Muncie JM, Weaver VM
Membrane Tension Locks In Pluripotency.
Cell stem cell, 2021-02-04.
Hayward MK, Louise Jones J, Hall A, King L, Ironside AJ, Nelson AC, Shelley Hwang E, Weaver VM
Derivation of a nuclear heterogeneity image index to grade DCIS.
Computational and structural biotechnology journal, 2020-12-03.
Barkovskaya A, Buffone A, Žídek M, Weaver VM
Proteoglycans as Mediators of Cancer Tissue Mechanics.
Frontiers in cell and developmental biology, 2020-11-30.
Maller O, Drain AP, Barrett AS, Borgquist S, Ruffell B, Zakharevich I, Pham TT, Gruosso T, Kuasne H, Lakins JN, Acerbi I, Barnes JM, Nemkov T, Chauhan A, Gruenberg J, Nasir A, Bjarnadottir O, Werb Z, Kabos P, Chen YY, Hwang ES, Park M, Coussens LM, Nelson AC, Hansen KC, Weaver VM
Tumour-associated macrophages drive stromal cell-dependent collagen crosslinking and stiffening to promote breast cancer aggression.
Nature materials, 2020-11-30.
Muncie JM, Ayad NME, Lakins JN, Xue X, Fu J, Weaver VM
Mechanical Tension Promotes Formation of Gastrulation-like Nodes and Patterns Mesoderm Specification in Human Embryonic Stem Cells.
Developmental cell, 2020-11-10.
Weaver VM, Bissell MJ
Zena Werb (1945-2020): Mourning the loss of a tissue microenvironment icon.
Proceedings of the National Academy of Sciences of the United States of America, 2020-10-29.
Barcellos-Hoff MH, Weaver VM
In Memoriam - Zena Werb 1945-2020.
Journal of mammary gland biology and neoplasia, 2020-09-30.
Jiang H, Torphy RJ, Steiger K, Hongo H, Ritchie AJ, Kriegsmann M, Horst D, Umetsu SE, Joseph NM, McGregor K, Pishvaian MJ, Blais EM, Lu B, Li M, Hollingsworth M, Stashko C, Volmar K, Yeh JJ, Weaver VM, Wang ZJ, Tempero MA, Weichert W, Collisson EA
Pancreatic ductal adenocarcinoma progression is restrained by stromal matrix.
The Journal of clinical investigation, 2020-08-04.
Alsamman S, Christenson SA, Yu A, Ayad NME, Mooring MS, Segal JM, Hu JK, Schaub JR, Ho SS, Rao V, Marlow MM, Turner SM, Sedki M, Pantano L, Ghoshal S, Ferreira DDS, Ma HY, Duwaerts CC, Espanol-Suner R, Wei L, Newcomb B, Mileva I, Canals D, Hannun YA, Chung RT, Mattis AN, Fuchs BC, Tager AM, Yimlamai D, Weaver VM, Mullen AC, Sheppard D, Chen JY
Targeting acid ceramidase inhibits YAP/TAZ signaling to reduce fibrosis in mice.
Science translational medicine, 2020-08-19.
Egeblad M, Coussens LM, Weaver VM
Zena Werb 1945-2020.
Nature cancer, 2020-08-01.
Northey JJ, Barrett AS, Acerbi I, Hayward MK, Talamantes S, Dean IS, Mouw JK, Ponik SM, Lakins JN, Huang PJ, Wu J, Shi Q, Samson S, Keely PJ, Mukhtar RA, Liphardt JT, Shepherd JA, Hwang ES, Chen YY, Hansen KC, Littlepage LE, Weaver VM
Stiff stroma increases breast cancer risk by inducing the oncogene ZNF217.
The Journal of clinical investigation, 2020-07-28.
Piersma B, Hayward MK, Weaver VM
Fibrosis and cancer: A strained relationship.
Biochimica et biophysica acta. Reviews on cancer, 2020-03-05.
Ayad NME, Weaver VM
Tension in tumour cells keeps metabolism high.
Nature, 2020-02-01.
Buffone A, Weaver VM
Don't sugarcoat it: How glycocalyx composition influences cancer progression.
The Journal of cell biology, 2020-01-06.
Sahai E, Astsaturov I, Cukierman E, DeNardo DG, Egeblad M, Evans RM, Fearon D, Greten FR, Hingorani SR, Hunter T, Hynes RO, Jain RK, Janowitz T, Jorgensen C, Kimmelman AC, Kolonin MG, Maki RG, Powers RS, Puré E, Ramirez DC, Scherz-Shouval R, Sherman MH, Stewart S, Tlsty TD, Tuveson DA, Watt FM, Weaver V, Weeraratna AT, Werb Z
A framework for advancing our understanding of cancer-associated fibroblasts.
Nature reviews. Cancer, 2020-01-24.
Eliazer S, Muncie JM, Christensen J, Sun X, D'Urso RS, Weaver VM, Brack AS
Wnt4 from the Niche Controls the Mechano-Properties and Quiescent State of Muscle Stem Cells.
Cell stem cell, 2019-09-03.
Muncie JM, Falcón-Banchs R, Lakins JN, Sohn LL, Weaver VM
Patterning the Geometry of Human Embryonic Stem Cell Colonies on Compliant Substrates to Control Tissue-Level Mechanics.
Journal of visualized experiments : JoVE, 2019-09-28.
Zheng Y, Xue X, Shao Y, Wang S, Esfahani SN, Li Z, Muncie JM, Lakins JN, Weaver VM, Gumucio DL, Fu J
Controlled modelling of human epiblast and amnion development using stem cells.
Nature, 2019-09-11.
Ayad NME, Kaushik S, Weaver VM
Tissue mechanics, an important regulator of development and disease.
Philosophical transactions of the Royal Society of London. Series B, Biological sciences, 2019-07-01.
Kai F, Drain AP, Weaver VM
The Extracellular Matrix Modulates the Metastatic Journey.
Developmental cell, 2019-05-06.
Libby AR, Joy DA, So PL, Mandegar MA, Muncie JM, Mendoza-Camacho FN, Weaver VM, Conklin BR, McDevitt TC
Spatiotemporal mosaic self-patterning of pluripotent stem cells using CRISPR interference.
eLife, 2018-10-09.
Barnes JM, Kaushik S, Bainer RO, Sa JK, Woods EC, Kai F, Przybyla L, Lee M, Lee HW, Tung JC, Maller O, Barrett AS, Lu KV, Lakins JN, Hansen KC, Obernier K, Alvarez-Buylla A, Bergers G, Phillips JJ, Nam DH, Bertozzi CR, Weaver VM
A tension-mediated glycocalyx-integrin feedback loop promotes mesenchymal-like glioblastoma.
Nature cell biology, 2018-09-10.
Sampayo RG, Toscani AM, Rubashkin MG, Thi K, Masullo LA, Violi IL, Lakins JN, Cáceres A, Hines WC, Coluccio Leskow F, Stefani FD, Chialvo DR, Bissell MJ, Weaver VM, Simian M
Fibronectin rescues estrogen receptor a from lysosomal degradation in breast cancer cells.
The Journal of cell biology, 2018-07-06.
Tharp KM, Weaver VM
Modeling Tissue Polarity in Context.
Journal of molecular biology, 2018-07-25.
Barrett AS, Maller O, Pickup MW, Weaver VM, Hansen KC
Compartment resolved proteomics reveals a dynamic matrisome in a biomechanically driven model of pancreatic ductal adenocarcinoma.
Journal of immunology and regenerative medicine, 2018-04-25.
Muncie JM, Weaver VM
The Physical and Biochemical Properties of the Extracellular Matrix Regulate Cell Fate.
Current topics in developmental biology, 2018-03-21.
Samson S, Northey JJ, Plaks V, Baas C, Dean I, LaBarge MA, Goga A, Van't Veer LJ, Weaver VM
New Horizons in Advocacy Engaged Physical Sciences and Oncology Research.
Trends in cancer, 2018-03-15.
Ilkhanizadeh S, Sabelström H, Miroshnikova YA, Frantz A, Zhu W, Idilli A, Lakins JN, Schmidt C, Quigley DA, Fenster T, Yuan E, Trzeciak JR, Saxena S, Lindberg OR, Mouw JK, Burdick JA, Magnitsky S, Berger MS, Phillips JJ, Arosio D, Sun D, Weaver VM, Weiss WA, Persson AI
Antisecretory Factor-Mediated Inhibition of Cell Volume Dynamics Produces Antitumor Activity in Glioblastoma.
Molecular cancer research : MCR, 2018-02-05.
Northcott JM, Dean IS, Mouw JK, Weaver VM
Feeling Stress: The Mechanics of Cancer Progression and Aggression.
Frontiers in cell and developmental biology, 2018-02-28.
Takai K, Drain AP, Lawson DA, Littlepage LE, Karpuj M, Kessenbrock K, Le A, Inoue K, Weaver VM, Werb Z
Discoidin domain receptor 1 (DDR1) ablation promotes tissue fibrosis and hypoxia to induce aggressive basal-like breast cancers.
Genes & development, 2018-02-01.
Ramakrishnan N, Sreeja KK, Roychoudhury A, Eckmann DM, Ayyaswamy PS, Baumgart T, Pucadyil T, Patil S, Weaver VM, Radhakrishnan R
Excess area dependent scaling behavior of nano-sized membrane tethers.
Physical biology, 2018-01-11.
Woods EC, Kai F, Barnes JM, Pedram K, Pickup MW, Hollander MJ, Weaver VM, Bertozzi CR
A bulky glycocalyx fosters metastasis formation by promoting G1 cell cycle progression.
eLife, 2017-12-21.
Northey JJ, Przybyla L, Weaver VM
Tissue Force Programs Cell Fate and Tumor Aggression.
Cancer discovery, 2017-10-16.
Miroshnikova YA, Rozenberg GI, Cassereau L, Pickup M, Mouw JK, Ou G, Templeman KL, Hannachi EI, Gooch KJ, Sarang-Sieminski AL, García AJ, Weaver VM
a5ß1-Integrin promotes tension-dependent mammary epithelial cell invasion by engaging the fibronectin synergy site.
Molecular biology of the cell, 2017-09-06.
Pickup MW, Owens P, Gorska AE, Chytil A, Ye F, Shi C, Weaver VM, Kalluri R, Moses HL, Novitskiy SV
Development of Aggressive Pancreatic Ductal Adenocarcinomas Depends on Granulocyte Colony Stimulating Factor Secretion in Carcinoma Cells.
Cancer immunology research, 2017-08-03.
Weaver VM
Cell and tissue mechanics: the new cell biology frontier.
Molecular biology of the cell, 2017-07-07.
Salvador F, Martin A, López-Menéndez C, Moreno-Bueno G, Santos V, Vázquez-Naharro A, Santamaria PG, Morales S, Dubus PR, Muinelo-Romay L, López-López R, Tung JC, Weaver VM, Portillo F, Cano A
Lysyl Oxidase-like Protein LOXL2 Promotes Lung Metastasis of Breast Cancer.
Cancer research, 2017-07-18.
Cai E, Marchuk K, Beemiller P, Beppler C, Rubashkin MG, Weaver VM, Gérard A, Liu TL, Chen BC, Betzig E, Bartumeus F, Krummel MF
Visualizing dynamic microvillar search and stabilization during ligand detection by T cells.
Science (New York, N.Y.), 2017-05-12.
Khuc E, Bainer R, Wolf M, Clay SM, Weisenberger DJ, Kemmer J, Weaver VM, Hwang DG, Chan MF
Comprehensive characterization of DNA methylation changes in Fuchs endothelial corneal dystrophy.
PloS one, 2017-04-06.
Mekhdjian AH, Kai F, Rubashkin MG, Prahl LS, Przybyla LM, McGregor AL, Bell ES, Barnes JM, DuFort CC, Ou G, Chang AC, Cassereau L, Tan SJ, Pickup MW, Lakins JN, Ye X, Davidson MW, Lammerding J, Odde DJ, Dunn AR, Weaver VM
Integrin-mediated traction force enhances paxillin molecular associations and adhesion dynamics that increase the invasiveness of tumor cells into a three-dimensional extracellular matrix.
Molecular biology of the cell, 2017-04-05.
Oudin MJ, Weaver VM
Physical and Chemical Gradients in the Tumor Microenvironment Regulate Tumor Cell Invasion, Migration, and Metastasis.
Cold Spring Harbor symposia on quantitative biology, 2017-04-19.
Barnes JM, Przybyla L, Weaver VM
Tissue mechanics regulate brain development, homeostasis and disease.
Journal of cell science, 2017-01-01.
Chang TT, Thakar D, Weaver VM
Force-dependent breaching of the basement membrane.
Matrix biology : journal of the International Society for Matrix Biology, 2016-12-23.
Takai K, Le A, Weaver VM, Werb Z
Targeting the cancer-associated fibroblasts as a treatment in triple-negative breast cancer.
Oncotarget, 2016-12-13.
Kaushik S, Pickup MW, Weaver VM
From transformation to metastasis: deconstructing the extracellular matrix in breast cancer.
Cancer metastasis reviews, 2016-12-01.
Miroshnikova YA, Mouw JK, Barnes JM, Pickup MW, Lakins JN, Kim Y, Lobo K, Persson AI, Reis GF, McKnight TR, Holland EC, Phillips JJ, Weaver VM
Tissue mechanics promote IDH1-dependent HIF1a-tenascin C feedback to regulate glioblastoma aggression.
Nature cell biology, 2016-11-07.
Chan TS, Hsu CC, Pai VC, Liao WY, Huang SS, Tan KT, Yen CJ, Hsu SC, Chen WY, Shan YS, Li CR, Lee MT, Jiang KY, Chu JM, Lien GS, Weaver VM, Tsai KK
Metronomic chemotherapy prevents therapy-induced stromal activation and induction of tumor-initiating cells.
The Journal of experimental medicine, 2016-11-23.
Gilbert PM, Weaver VM
Cellular adaptation to biomechanical stress across length scales in tissue homeostasis and disease.
Seminars in cell & developmental biology, 2016-09-15.
Przybyla L, Lakins JN, Weaver VM
Tissue Mechanics Orchestrate Wnt-Dependent Human Embryonic Stem Cell Differentiation.
Cell stem cell, 2016-07-21.
Przybyla L, Muncie JM, Weaver VM
Mechanical Control of Epithelial-to-Mesenchymal Transitions in Development and Cancer.
Annual review of cell and developmental biology, 2016-06-08.
Ou G, Thakar D, Tung JC, Miroshnikova YA, Dufort CC, Gutierrez E, Groisman A, Weaver VM
Visualizing mechanical modulation of nanoscale organization of cell-matrix adhesions.
Integrative biology : quantitative biosciences from nano to macro, 2016-06-23.
Bhagawati M, Rubashkin MG, Lee JP, Ananthanarayanan B, Weaver VM, Kumar S
Site-Specific Modulation of Charge Controls the Structure and Stimulus Responsiveness of Intrinsically Disordered Peptide Brushes.
Langmuir : the ACS journal of surfaces and colloids, 2016-06-02.
Kai F, Laklai H, Weaver VM
Force Matters: Biomechanical Regulation of Cell Invasion and Migration in Disease.
Trends in cell biology, 2016-04-04.
Laklai H, Miroshnikova YA, Pickup MW, Collisson EA, Kim GE, Barrett AS, Hill RC, Lakins JN, Schlaepfer DD, Mouw JK, LeBleu VS, Roy N, Novitskiy SV, Johansen JS, Poli V, Kalluri R, Iacobuzio-Donahue CA, Wood LD, Hebrok M, Hansen K, Moses HL, Weaver VM
Genotype tunes pancreatic ductal adenocarcinoma tissue tension to induce matricellular fibrosis and tumor progression.
Nature medicine, 2016-04-18.
Desai SS, Tung JC, Zhou VX, Grenert JP, Malato Y, Rezvani M, Español-Suñer R, Willenbring H, Weaver VM, Chang TT
Physiological ranges of matrix rigidity modulate primary mouse hepatocyte function in part through hepatocyte nuclear factor 4 alpha.
Hepatology (Baltimore, Md.), 2016-03-09.
Le LT, Cazares O, Mouw JK, Chatterjee S, Macias H, Moran A, Ramos J, Keely PJ, Weaver VM, Hinck L
Loss of miR-203 regulates cell shape and matrix adhesion through ROBO1/Rac/FAK in response to stiffness.
The Journal of cell biology, 2016-03-14.
Özdemir BC, Pentcheva-Hoang T, Carstens JL, Zheng X, Wu CC, Simpson TR, Laklai H, Sugimoto H, Kahlert C, Novitskiy SV, De Jesus-Acosta A, Sharma P, Heidari P, Mahmood U, Chin L, Moses HL, Weaver VM, Maitra A, Allison JP, LeBleu VS, Kalluri R
Depletion of Carcinoma-Associated Fibroblasts and Fibrosis Induces Immunosuppression and Accelerates Pancreas Cancer with Reduced Survival.
Cancer cell, 2015-12-14.
Ou G, Weaver VM
Tumor-induced solid stress activates ß-catenin signaling to drive malignant behavior in normal, tumor-adjacent cells.
BioEssays : news and reviews in molecular, cellular and developmental biology, 2015-10-06.
Lin CH, Pelissier FA, Zhang H, Lakins J, Weaver VM, Park C, LaBarge MA
Microenvironment rigidity modulates responses to the HER2 receptor tyrosine kinase inhibitor lapatinib via YAP and TAZ transcription factors.
Molecular biology of the cell, 2015-09-02.
Przybyla L, Lakins JN, Sunyer R, Trepat X, Weaver VM
Monitoring developmental force distributions in reconstituted embryonic epithelia.
Methods (San Diego, Calif.), 2015-09-02.
Lau J, Ilkhanizadeh S, Wang S, Miroshnikova YA, Salvatierra NA, Wong RA, Schmidt C, Weaver VM, Weiss WA, Persson AI
STAT3 Blockade Inhibits Radiation-Induced Malignant Progression in Glioma.
Cancer research, 2015-08-17.
Acerbi I, Cassereau L, Dean I, Shi Q, Au A, Park C, Chen YY, Liphardt J, Hwang ES, Weaver VM
Human breast cancer invasion and aggression correlates with ECM stiffening and immune cell infiltration.
Integrative biology : quantitative biosciences from nano to macro, 2015-05-11.
Northcott JM, Northey JJ, Barnes JM, Weaver VM
Fighting the force: Potential of homeobox genes for tumor microenvironment regulation.
Biochimica et biophysica acta, 2015-03-24.
Tung JC, Barnes JM, Desai SR, Sistrunk C, Conklin MW, Schedin P, Eliceiri KW, Keely PJ, Seewaldt VL, Weaver VM
Tumor mechanics and metabolic dysfunction.
Free radical biology & medicine, 2014-12-19.
Pickup MW, Mouw JK, Weaver VM
The extracellular matrix modulates the hallmarks of cancer.
EMBO reports, 2014-11-08.
Mouw JK, Ou G, Weaver VM
Extracellular matrix assembly: a multiscale deconstruction.
Nature reviews. Molecular cell biology, 2014-11-05.
Cassereau L, Miroshnikova YA, Ou G, Lakins J, Weaver VM
A 3D tension bioreactor platform to study the interplay between ECM stiffness and tumor phenotype.
Journal of biotechnology, 2014-11-27.
Weaver VM
The microenvironment matters.
Molecular biology of the cell, 2014-11-01.
Rubashkin MG, Cassereau L, Bainer R, DuFort CC, Yui Y, Ou G, Paszek MJ, Davidson MW, Chen YY, Weaver VM
Force engages vinculin and promotes tumor progression by enhancing PI3K activation of phosphatidylinositol (3,4,5)-triphosphate.
Cancer research, 2014-09-01.
Venugopalan G, Camarillo DB, Webster KD, Reber CD, Sethian JA, Weaver VM, Fletcher DA, El-Samad H, Rycroft CH
Multicellular architecture of malignant breast epithelia influences mechanics.
PloS one, 2014-08-11.
Paszek MJ, DuFort CC, Rossier O, Bainer R, Mouw JK, Godula K, Hudak JE, Lakins JN, Wijekoon AC, Cassereau L, Rubashkin MG, Magbanua MJ, Thorn KS, Davidson MW, Rugo HS, Park JW, Hammer DA, Giannone G, Bertozzi CR, Weaver VM
The cancer glycocalyx mechanically primes integrin-mediated growth and survival.
Nature, 2014-06-25.
Özdemir BC, Pentcheva-Hoang T, Carstens JL, Zheng X, Wu CC, Simpson TR, Laklai H, Sugimoto H, Kahlert C, Novitskiy SV, De Jesus-Acosta A, Sharma P, Heidari P, Mahmood U, Chin L, Moses HL, Weaver VM, Maitra A, Allison JP, LeBleu VS, Kalluri R
Depletion of carcinoma-associated fibroblasts and fibrosis induces immunosuppression and accelerates pancreas cancer with reduced survival.
Cancer cell, 2014-05-22.
Michor F, Weaver VM
Understanding tissue context influences on intratumour heterogeneity.
Nature cell biology, 2014-04-01.
Rubashkin MG, Ou G, Weaver VM
Deconstructing signaling in three dimensions.
Biochemistry, 2014-03-28.
Mouw JK, Yui Y, Damiano L, Bainer RO, Lakins JN, Acerbi I, Ou G, Wijekoon AC, Levental KR, Gilbert PM, Hwang ES, Chen YY, Weaver VM
Tissue mechanics modulate microRNA-dependent PTEN expression to regulate malignant progression.
Nature medicine, 2014-03-16.
Shi Q, Ghosh RP, Engelke H, Rycroft CH, Cassereau L, Sethian JA, Weaver VM, Liphardt JT
Rapid disorganization of mechanically interacting systems of mammary acini.
Proceedings of the National Academy of Sciences of the United States of America, 2013-12-30.
Maller O, Hansen KC, Lyons TR, Acerbi I, Weaver VM, Prekeris R, Tan AC, Schedin P
Collagen architecture in pregnancy-induced protection from breast cancer.
Journal of cell science, Sep-15-2013;126(Pt 18):4108-10.  Epub 2013 Jul 10.
Bainer R, Weaver V
Cell biology. Strength under tension.
Science (New York, N.Y.), 2013-08-30.
Pickup MW, Laklai H, Acerbi I, Owens P, Gorska AE, Chytil A, Aakre M, Weaver VM, Moses HL
Stromally derived lysyl oxidase promotes metastasis of transforming growth factor-ß-deficient mouse mammary carcinomas.
Cancer research, 2013-07-15.
Maller O, Hansen KC, Lyons TR, Acerbi I, Weaver VM, Prekeris R, Tan AC, Schedin P
Collagen architecture in pregnancy-induced protection from breast cancer.
Journal of cell science, 2013-07-10.
Damiano L, Stewart KM, Cohet N, Mouw JK, Lakins JN, Debnath J, Reisman D, Nickerson JA, Imbalzano AN, Weaver VM
Oncogenic targeting of BRM drives malignancy through C/EBPß-dependent induction of a5 integrin.
Oncogene, 2013-06-17.
Maller O, DuFort CC, Weaver VM
YAP forces fibroblasts to feel the tension.
Nature cell biology, 2013-06-01.
Tang Y, Rowe RG, Botvinick EL, Kurup A, Putnam AJ, Seiki M, Weaver VM, Keller ET, Goldstein S, Dai J, Begun D, Saunders T, Weiss SJ
MT1-MMP-dependent control of skeletal stem cell commitment via a ß1-integrin/YAP/TAZ signaling axis.
Developmental cell, 2013-05-16.
Agus DB, Alexander JF, Arap W, Ashili S, Aslan JE, Austin RH, Backman V, Bethel KJ, Bonneau R, Chen WC, Chen-Tanyolac C, Choi NC, Curley SA, Dallas M, Damania D, Davies PC, Decuzzi P, Dickinson L, Estevez-Salmeron L, Estrella V, Ferrari M, Fischbach C, Foo J, Fraley SI, Frantz C, Fuhrmann A, Gascard P, Gatenby RA, Geng Y, Gerecht S, Gillies RJ, Godin B, Grady WM, Greenfield A, Hemphill C, Hempstead BL, Hielscher A, Hillis WD, Holland EC, Ibrahim-Hashim A, Jacks T, Johnson RH, Joo A, Katz JE, Kelbauskas L, Kesselman C, King MR, Konstantopoulos K, Kraning-Rush CM, Kuhn P, Kung K, Kwee B, Lakins JN, Lambert G, Liao D, Licht JD, Liphardt JT, Liu L, Lloyd MC, Lyubimova A, Mallick P, Marko J, McCarty OJ, Meldrum DR, Michor F, Mumenthaler SM, Nandakumar V, O'Halloran TV, Oh S, Pasqualini R, Paszek MJ, Philips KG, Poultney CS, Rana K, Reinhart-King CA, Ros R, Semenza GL, Senechal P, Shuler ML, Srinivasan S, Staunton JR, Stypula Y, Subramanian H, Tlsty TD, Tormoen GW, Tseng Y, van Oudenaarden A, Verbridge SS, Wan JC, Weaver VM, Widom J, Will C, Wirtz D, Wojtkowiak J, Wu PH
A physical sciences network characterization of non-tumorigenic and metastatic cells.
Scientific reports, 2013-01-01.
Li CR, Su JJ, Wang WY, Lee MT, Wang TY, Jiang KY, Li CF, Hsu JM, Chen CK, Chen M, Jiang SS, Weaver VM, Tsai KK
Molecular profiling of prostatic acinar morphogenesis identifies PDCD4 and KLF6 as tissue architecture-specific prognostic markers in prostate cancer.
The American journal of pathology, 2012-12-04.
Paszek MJ, DuFort CC, Rubashkin MG, Davidson MW, Thorn KS, Liphardt JT, Weaver VM
Scanning angle interference microscopy reveals cell dynamics at the nanoscale.
Nature methods, 2012-07-01.
Cassereau L, DuFort CC, Weaver VM
Morphogenesis: Laying down the tracks.
Nature materials, 2012-05-22.
Lu P, Weaver VM, Werb Z
The extracellular matrix: a dynamic niche in cancer progression.
The Journal of cell biology, 2012-02-20.
Lakins JN, Chin AR, Weaver VM
Exploring the link between human embryonic stem cell organization and fate using tension-calibrated extracellular matrix functionalized polyacrylamide gels.
Methods in molecular biology (Clifton, N.J.), 2012-01-01.
Lu P, Takai K, Weaver VM, Werb Z
Extracellular matrix degradation and remodeling in development and disease.
Cold Spring Harbor perspectives in biology, 2011-12-01.
Lopez JI, Kang I, You WK, McDonald DM, Weaver VM
In situ force mapping of mammary gland transformation.
Integrative biology : quantitative biosciences from nano to macro, 2011-08-15.
Samuel MS, Lopez JI, McGhee EJ, Croft DR, Strachan D, Timpson P, Munro J, Schröder E, Zhou J, Brunton VG, Barker N, Clevers H, Sansom OJ, Anderson KI, Weaver VM, Olson MF
Actomyosin-mediated cellular tension drives increased tissue stiffness and ß-catenin activation to induce epidermal hyperplasia and tumor growth.
Cancer cell, 2011-06-14.
Weaver V
Valerie Weaver: overcoming cancer's stiff resistance. Interview by Caitlin Sedwick.
The Journal of cell biology, 2011-05-30.
DuFort CC, Paszek MJ, Weaver VM
Balancing forces: architectural control of mechanotransduction.
Nature reviews. Molecular cell biology, 2011-05-01.
Dvorak HF, Weaver VM, Tlsty TD, Bergers G
Tumor microenvironment and progression.
Journal of surgical oncology, 2011-05-01.
Miroshnikova YA, Jorgens DM, Spirio L, Auer M, Sarang-Sieminski AL, Weaver VM
Engineering strategies to recapitulate epithelial morphogenesis within synthetic three-dimensional extracellular matrix with tunable mechanical properties.
Physical biology, 2011-03-25.
Frantz C, Stewart KM, Weaver VM
The extracellular matrix at a glance.
Journal of cell science, 2010-12-15.
Yu H, Mouw JK, Weaver VM
Forcing form and function: biomechanical regulation of tumor evolution.
Trends in cell biology, 2010-10-01.
Brown XQ, Bartolak-Suki E, Williams C, Walker ML, Weaver VM, Wong JY
Effect of substrate stiffness and PDGF on the behavior of vascular smooth muscle cells: implications for atherosclerosis.
Journal of cellular physiology, 2010-10-01.
Egeblad M, Rasch MG, Weaver VM
Dynamic interplay between the collagen scaffold and tumor evolution.
Current opinion in cell biology, 2010-09-06.
Cohet N, Stewart KM, Mudhasani R, Asirvatham AJ, Mallappa C, Imbalzano KM, Weaver VM, Imbalzano AN, Nickerson JA
SWI/SNF chromatin remodeling enzyme ATPases promote cell proliferation in normal mammary epithelial cells.
Journal of cellular physiology, 2010-06-01.
Gilbert PM, Mouw JK, Unger MA, Lakins JN, Gbegnon MK, Clemmer VB, Benezra M, Licht JD, Boudreau NJ, Tsai KK, Welm AL, Feldman MD, Weber BL, Weaver VM
HOXA9 regulates BRCA1 expression to modulate human breast tumor phenotype.
The Journal of clinical investigation, 2010-04-12.
Paszek M, Weaver V
Biophysics. Enforcing order on signaling.
Science (New York, N.Y.), 2010-03-12.
Vogel V
Journal club. A bioengineer discusses how mechanical forces in tissues may promote malignancy.
Nature, Feb-4-2010;463(7281):591.
Ng MR, Brugge JS
A stiff blow from the stroma: collagen crosslinking drives tumor progression.
Cancer cell, Dec-8-2009;16(6):455-7.
Paszek MJ, Boettiger D, Weaver VM, Hammer DA
Integrin clustering is driven by mechanical resistance from the glycocalyx and the substrate.
PLoS computational biology, 2009-12-11.
Levental KR, Yu H, Kass L, Lakins JN, Egeblad M, Erler JT, Fong SF, Csiszar K, Giaccia A, Weninger W, Yamauchi M, Gasser DL, Weaver VM
Matrix crosslinking forces tumor progression by enhancing integrin signaling.
Cell, 2009-11-25.
Kumar S, Weaver VM
Mechanics, malignancy, and metastasis: the force journey of a tumor cell.
Cancer metastasis reviews, 2009-06-01.
Gehler S, Baldassarre M, Lad Y, Leight JL, Wozniak MA, Riching KM, Eliceiri KW, Weaver VM, Calderwood DA, Keely PJ
Filamin A-beta1 integrin complex tunes epithelial cell response to matrix tension.
Molecular biology of the cell, 2009-05-20.
Hansma P, Yu H, Schultz D, Rodriguez A, Yurtsev EA, Orr J, Tang S, Miller J, Wallace J, Zok F, Li C, Souza R, Proctor A, Brimer D, Nogues-Solan X, Mellbovsky L, Peña MJ, Diez-Ferrer O, Mathews P, Randall C, Kuo A, Chen C, Peters M, Kohn D, Buckley J, Li X, Pruitt L, Diez-Perez A, Alliston T, Weaver V, Lotz J
The tissue diagnostic instrument.
The Review of scientific instruments, 2009-05-01.
Engler AJ, Humbert PO, Wehrle-Haller B, Weaver VM
Multiscale modeling of form and function.
Science (New York, N.Y.), 2009-04-10.
Vasilatos SN, Broadwater G, Barry WT, Baker JC, Lem S, Dietze EC, Bean GR, Bryson AD, Pilie PG, Goldenberg V, Skaar D, Paisie C, Torres-Hernandez A, Grant TL, Wilke LG, Ibarra-Drendall C, Ostrander JH, D'Amato NC, Zalles C, Jirtle R, Weaver VM, Seewaldt VL
CpG island tumor suppressor promoter methylation in non-BRCA-associated early mammary carcinogenesis.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, 2009-03-03.
Butcher DT, Alliston T, Weaver VM
A tense situation: forcing tumour progression.
Nature reviews. Cancer, 2009-02-01.
Lopez JI, Mouw JK, Weaver VM
Biomechanical regulation of cell orientation and fate.
Oncogene, 2008-11-24.
Erler JT, Weaver VM
Three-dimensional context regulation of metastasis.
Clinical & experimental metastasis, 2008-09-24.
Rizki A, Weaver VM, Lee SY, Rozenberg GI, Chin K, Myers CA, Bascom JL, Mott JD, Semeiks JR, Grate LR, Mian IS, Borowsky AD, Jensen RA, Idowu MO, Chen F, Chen DJ, Petersen OW, Gray JW, Bissell MJ
A human breast cell model of preinvasive to invasive transition.
Cancer research, 2008-03-01.
Fournier AK, Campbell LE, Castagnino P, Liu WF, Chung BM, Weaver VM, Chen CS, Assoian RK
Rac-dependent cyclin D1 gene expression regulated by cadherin- and integrin-mediated adhesion.
Journal of cell science, 2008-01-15.
Hebner C, Weaver VM, Debnath J
Modeling morphogenesis and oncogenesis in three-dimensional breast epithelial cultures.
Annual review of pathology, 2008-01-01.
Yee KL, Weaver VM, Hammer DA
Integrin-mediated signalling through the MAP-kinase pathway.
IET systems biology, 2008-01-01.
Friedland JC, Lakins JN, Kazanietz MG, Chernoff J, Boettiger D, Weaver VM
alpha6beta4 integrin activates Rac-dependent p21-activated kinase 1 to drive NF-kappaB-dependent resistance to apoptosis in 3D mammary acini.
Journal of cell science, 2007-10-02.
Weaver V, Werb Z
G'rab'bing the microenvironment for invasion.
Developmental cell, 2007-10-01.
Kass L, Erler JT, Dembo M, Weaver VM
Mammary epithelial cell: influence of extracellular matrix composition and organization during development and tumorigenesis.
The international journal of biochemistry & cell biology, 2007-07-19.
Johnson KR, Leight JL, Weaver VM
Demystifying the effects of a three-dimensional microenvironment in tissue morphogenesis.
Methods in cell biology, 2007-01-01.
Underwood JM, Imbalzano KM, Weaver VM, Fischer AH, Imbalzano AN, Nickerson JA
The ultrastructure of MCF-10A acini.
Journal of cellular physiology, 2006-07-01.
Boudreau N, Weaver V
Forcing the third dimension.
Cell, 2006-05-05.
Yan Y, Weaver VM, Blair IA
Analysis of protein expression during oxidative stress in breast epithelial cells using a stable isotope labeled proteome internal standard.
Journal of proteome research, 2005-11-01.
Paszek MJ, Zahir N, Johnson KR, Lakins JN, Rozenberg GI, Gefen A, Reinhart-King CA, Margulies SS, Dembo M, Boettiger D, Hammer DA, Weaver VM
Tensional homeostasis and the malignant phenotype.
Cancer cell, 2005-09-01.
Yang C, Liu Y, Leskow FC, Weaver VM, Kazanietz MG
Rac-GAP-dependent inhibition of breast cancer cell proliferation by {beta}2-chimerin.
The Journal of biological chemistry, 2005-04-29.
Cowden Dahl KD, Robertson SE, Weaver VM, Simon MC
Hypoxia-inducible factor regulates alphavbeta3 integrin cell surface expression.
Molecular biology of the cell, 2005-02-02.
Yeung T, Georges PC, Flanagan LA, Marg B, Ortiz M, Funaki M, Zahir N, Ming W, Weaver V, Janmey PA
Effects of substrate stiffness on cell morphology, cytoskeletal structure, and adhesion.
Cell motility and the cytoskeleton, 2005-01-01.
Paszek MJ, Weaver VM
The tension mounts: mechanics meets morphogenesis and malignancy.
Journal of mammary gland biology and neoplasia, 2004-10-01.
Weaver VM, Gilbert P
Watch thy neighbor: cancer is a communal affair.
Journal of cell science, 2004-03-15.
Zahir N, Weaver VM
Death in the third dimension: apoptosis regulation and tissue architecture.
Current opinion in genetics & development, 2004-02-01.
Zahir N, Lakins JN, Russell A, Ming W, Chatterjee C, Rozenberg GI, Marinkovich MP, Weaver VM
Autocrine laminin-5 ligates alpha6beta4 integrin and activates RAC and NFkappaB to mediate anchorage-independent survival of mammary tumors.
The Journal of cell biology, 2003-12-22.
Russell AJ, Fincher EF, Millman L, Smith R, Vela V, Waterman EA, Dey CN, Guide S, Weaver VM, Marinkovich MP
Alpha 6 beta 4 integrin regulates keratinocyte chemotaxis through differential GTPase activation and antagonism of alpha 3 beta 1 integrin.
Journal of cell science, 2003-07-15.
Unger M, Weaver VM
The tissue microenvironment as an epigenetic tumor modifier.
Methods in molecular biology (Clifton, N.J.), 2003-01-01.
Bissell MJ, Radisky DC, Rizki A, Weaver VM, Petersen OW
The organizing principle: microenvironmental influences in the normal and malignant breast.
Differentiation; research in biological diversity, 2002-12-01.
Weaver VM, Lelièvre S, Lakins JN, Chrenek MA, Jones JC, Giancotti F, Werb Z, Bissell MJ
beta4 integrin-dependent formation of polarized three-dimensional architecture confers resistance to apoptosis in normal and malignant mammary epithelium.
Cancer cell, 2002-09-01.
Weaver VM
Membrane-associated MMP regulators: novel cell adhesion tumor suppressor proteins?
Developmental cell, 2002-01-01.
Chrenek MA, Wong P, Weaver VM
Tumour-stromal interactions. Integrins and cell adhesions as modulators of mammary cell survival and transformation.
Breast cancer research : BCR, 2001-06-14.
Weaver VM, Buckley T, Groopman JD
Lack of specificity of trans,trans-muconic acid as a benzene biomarker after ingestion of sorbic acid-preserved foods.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, 2000-07-01.
Spancake KM, Anderson CB, Weaver VM, Matsunami N, Bissell MJ, White RL
E7-transduced human breast epithelial cells show partial differentiation in three-dimensional culture.
Cancer research, 1999-12-15.
Guerra-Vladusic FK, Scott G, Weaver V, Vladusic EA, Tsai MS, Benz CC, Lupu R
Constitutive expression of Heregulin induces apoptosis in an erbB-2 overexpressing breast cancer cell line SKBr-3.
International journal of oncology, 1999-11-01.
Bissell MJ, Weaver VM, Lelièvre SA, Wang F, Petersen OW, Schmeichel KL
Tissue structure, nuclear organization, and gene expression in normal and malignant breast.
Cancer research, 1999-04-01.
Weaver VM, Bissell MJ
Functional culture models to study mechanisms governing apoptosis in normal and malignant mammary epithelial cells.
Journal of mammary gland biology and neoplasia, 1999-04-01.
Wang F, Weaver VM, Petersen OW, Larabell CA, Dedhar S, Briand P, Lupu R, Bissell MJ
Reciprocal interactions between beta1-integrin and epidermal growth factor receptor in three-dimensional basement membrane breast cultures: a different perspective in epithelial biology.
Proceedings of the National Academy of Sciences of the United States of America, 1998-12-08.
Lelièvre SA, Weaver VM, Nickerson JA, Larabell CA, Bhaumik A, Petersen OW, Bissell MJ
Tissue phenotype depends on reciprocal interactions between the extracellular matrix and the structural organization of the nucleus.
Proceedings of the National Academy of Sciences of the United States of America, 1998-12-08.
Schmeichel KL, Weaver VM, Bissell MJ
Structural cues from the tissue microenvironment are essential determinants of the human mammary epithelial cell phenotype.
Journal of mammary gland biology and neoplasia, 1998-04-01.
Petersen OW, Rønnov-Jessen L, Weaver VM, Bissell MJ
Differentiation and cancer in the mammary gland: shedding light on an old dichotomy.
Advances in cancer research, 1998-01-01.
Weaver VM, Petersen OW, Wang F, Larabell CA, Briand P, Damsky C, Bissell MJ
Reversion of the malignant phenotype of human breast cells in three-dimensional culture and in vivo by integrin blocking antibodies.
The Journal of cell biology, 1997-04-07.
Weaver VM, Roskelley CD
Extracellular matrix: the central regulator of cell and tissue homeostasis.
Trends in cell biology, 1997-01-01.
Weaver VM, Carson CE, Walker PR, Chaly N, Lach B, Raymond Y, Brown DL, Sikorska M
Degradation of nuclear matrix and DNA cleavage in apoptotic thymocytes.
Journal of cell science, 1996-01-01.
Lelièvre S, Weaver VM, Bissell MJ
Extracellular matrix signaling from the cellular membrane skeleton to the nuclear skeleton: a model of gene regulation.
Recent progress in hormone research, 1996-01-01.
Weaver VM, Fischer AH, Peterson OW, Bissell MJ
The importance of the microenvironment in breast cancer progression: recapitulation of mammary tumorigenesis using a unique human mammary epithelial cell model and a three-dimensional culture assay.
Biochemistry and cell biology = Biochimie et biologie cellulaire, 1996-01-01.
Weaver VM, Howlett AR, Langton-Webster B, Petersen OW, Bissell MJ
The development of a functionally relevant cell culture model of progressive human breast cancer.
Seminars in cancer biology, 1995-06-01.
Weaver VM, Lach B, Walker PR, Sikorska M
Role of proteolysis in apoptosis: involvement of serine proteases in internucleosomal DNA fragmentation in immature thymocytes.
Biochemistry and cell biology = Biochimie et biologie cellulaire, 1993-09-01.
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